বৃহস্পতিবার, ১৮ জুলাই, ২০১৩

বুধবার, ১৭ জুলাই, ২০১৩

He Who Controls the Present Controls the Past? (Powerlineblog)

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4 Critical Lessons Comcast Learned From Taking Their Sales Mobile

[unable to retrieve full-text content]Comcast Business's sales managers and executives were already using Salesforce.com to view sales analytics and reports, prior to SMB 360. Now all the data captured in the app can easily be sent to the same cloud, via ...

Source: http://blogs.salesforce.com/company/2013/07/4-critical-lessons-comcast-learned-from-taking-their-sales-mobile.html

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Tracking Endangered Species by Sound

The coqu? llanero frog is a yellowish, peanut-sized creature that lives only in a single Puerto Rican wetland. It has a squeaky call that lies near the upper range of human hearing?ko-kee, ko-kee, which gives it its name?and as it squeaks, its jowl inflates like a balloon.

The frog was discovered in 2005. By 2012, it was already designated an endangered species. For the past five years, biologists at the University of Puerto Rico looking to track and protect the frog have been taking advantage of its unique call to monitor its status by sound. Using solar-powered iPods installed out in the Puerto Rican wetland, the scientists recorded the soundscape for 1 minute of every 10, 24 hours a day, and uploaded the data to their website, called the Automated Remote Biodiversity Monitoring Network (ARBIMON). They then used computer models to analyze the data and pick out the frog?s call.

It?s an unusual way to track the health of species, but one that could help researchers track other creatures in the wild: The approach could be used to observe any species that makes detectable noise. Furthermore, the website is not just for University of Puerto Rico researchers. Their system, which they report on in a study in the journal PeerJ, is open to everyone.

One Million Recordings

Chirp. Cheep. Buzz. Howl. Many animals reveal their presence by making noise, and recording the sounds of an environment creates an audio snapshot of many of the animals present. Recorders, like this team?s solar-powered iPods, can gather data from many places at once?much more data than even the most tireless field biologist could. Yet without systems to analyze the recordings, all this data would overwhelm researchers. That?s where ARBIMON comes in, says Gon?alo Ferraz, a biologist in Brazil whose lab uses the system to study the distributions of birds in the Amazon rainforest over time.

"Without ARBIMON, we would have to listen to thousands of hours of recordings in order to find where are the species that we want to locate," he says. Ferraz estimates that he has uploaded 5000 hours of recordings from 100 sites spread over nearly 200 square miles. "No one can sit through 5000 hours to look for a bird," says Ferraz. "With ARBIMON, we can have a computer do that searching for us very quickly."

Using a freely available application on the ARBIMON website, scientists can train the computer to recognize particular sounds from their data by uploading their recordings to the site and picking out several examples of the call for the computer to recognize. They can test the model on calls identified by human experts before moving on to the unknowns. "Once they get to a level where they feel confident that the model works well," says T. Mitchell Aide, a biologist at the University of Puerto Rico and lead author on the study, "they can run that model over hundreds of thousands of recordings in just a few hours."

ARBIMON also lets users share their data. Once a user has made a model to identify the call of a particular species, other users can then apply it to their data. "There are other software packages that can help you locate sounds in a recording. The new thing, and the really special thing about ARBIMON, is the ability to do that with a very large number of recordings at once and with many users," Ferraz says.

The site currently has 1.3 million 1-minute recordings. Over the past five years, researchers at the University of Puerto Rico have used the system to monitor the growth and decline of nine different species, including a poison dart frog, a howler monkey, a toucan, and the coqu? llanero. In their paper, the researchers report that the accuracy of ARBIMON?s models ranged from 79 to 99 percent. They found that the coqu? llanero populations seemed to decline from 2008 to 2012 but then rebounded last year.

Soundscape Library

Bioacoustics research?using sound analysis to study biology?is growing in popularity. For example, at the Bioacoustics Research Program at the Cornell Lab of Ornithology, scientists record sounds from whales, birds, and even elephants to learn about their diversity and communication. In the case of right whales, recording devices in shipping lanes off the Massachusetts coast allow Cornell to warn ships, lest they hit the endangered marine mammals. Cornell has also developed open-source software for analyzing animal sounds.

For the ARBIMON team, it?s about big data. It might not seem like a big deal to use these recordings to capture small fluctuations in the population of a frog, but the value of the data may change as time passes. Just as people see different things in a photograph, different scientists may reexamine old soundscapes and find different species. This is just the beginning of what Aide and colleagues hope will be a long-term record of biodiversity changes over time.

"We know that climate change and land-use change are changing the distribution and abundance of species, but we really don?t have good long-term measurements to say how they?re changing them," says Aide. "It would be really nice if we had 10 or 20 years of data that we could correlate with those changes in climate or deforestation to be able to show how the species are responding."

Source: http://www.popularmechanics.com/science/environment/tracking-endangered-specie-by-sound-15699559?src=rss

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মঙ্গলবার, ১৬ জুলাই, ২০১৩

Cancer researchers discover how BRCA mutation starts breast, ovarian cancers

[unable to retrieve full-text content]Scientists have solved a key piece in the puzzle of how BRCA1 gene mutations specifically predispose women to breast and ovarian cancers.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/lTax9haiRik/130715105118.htm

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HBT: News and notes from NL player availability

We?re in the middle of the NL player availabilities right now. The AL players will be made available in a few minutes. Somewhere right now there is a press conference about the Home Run Derby about to start. I?m not going to it because no one will be honest and say ?Well, I?m just gonna try to hit the ball really far and see what happens.? Who needs it?

These events are really for the folks who live on player quotes. We, obviously, don?t live on player quotes here at HBT. Unless they?re funny or controversial, of course. Then we go to town. But hearing and repeating that it?s an honor to be selected to the All-Star game and that they?re soaking it all in and they?d like to thank the fans who voted for them, well, that doesn?t do a ton for us. And I?ve never been the fan of ?ask the ballplayer the off-the-wall question!? school of journalism. Let?s leave that to gimmicky NFL people on the Super Bowl media day. Baseball and Triumph the Insult Comic Dog don?t mix that well.

Still, I went down and talked to some NL players and will talk to some AL players later because, heck, maybe someone would say something funny or controversial.?No one did to me (we?ll have to wait for stories from other reporters before we know for sure). I talked to Craig Kimbrel, Freddie Freeman and Andrew McCutchen. I was in a giant scrum around David Wright. I listened in on about a dozen other players being interviewed by other reporters. Among the highlights:

  • Jim Leyland had said earlier that, no surprise, Mariano Rivera will close the game out if necessary for the AL. I asked Kimbrel if Bruce Bochy had given any indication of the closer pecking order for the NL. I told him that he can answer quietly so Jason Grilli, sitting nearby, wouldn?t hear. Kimbrel said that he had no idea as he landed in New York about ten minutes ago and that I was like the fourth person he saw. When asked (by someone else) what his favorite park to pitch in was, he said ?the big ones.?
  • Freeman is disappointed by the fact that a day or two after he won the Final Vote thing he got hurt and now isn?t able to play. I almost think winning the vote for him was the most fun part about it, though. He figured he?d get killed by Puig in the voting and thinks his family back in Orange County stuffed the ballot box like crazy. I told him 19 million people voted for him. He laughed and said ?well, they helped.?
  • Jason Grilli is honored to be here. He also is unaware of any closer pecking order for the NL. Nor does he know if he?s the pitcher that Bruce Bochy has chosen to hold out of the game in case it goes 16 innings or something. I said that that?d probably be a starter. He said ?yeah.?
  • Unsurprisingly, Andrew McCutchen does not think the Pirates are going to collapse this year. I asked him if that question bugs him. He added that it?s way better to be asked about a team collapsing than never having the team be good enough to inspire that question in the first place. He didn?t put it quite like that ? he sort of got to that point after many words ? but that was the idea. I feel like it was one of those things that, back in the day before tape recorders and media scrums, one single sports writer ? a Damon Runyon type ? would craft it into a more pointed and witty quote and attribute it to McCutchen all the same.

Sometimes I?m kinda sad we don?t live in those days, actually. I like to think of ballplayers as witty raconteur-types. But they aren?t. They?re ballplayers and they?re paid to crush baseballs, not say witty things to sweaty reporters. And therein lies my basic issue with the game of player quotes.

Source: http://hardballtalk.nbcsports.com/2013/07/15/ballplayers-paid-to-hit-and-pitch-but-they-talk-to-the-media-anyway/related/

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রবিবার, ১৪ জুলাই, ২০১৩

What does college basketball NCAA stand for or mean?

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    A as a root word can mean not, without as in abyss ??? without bottom; achromatic ??? without...

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    Showing Emotions In Text Chat :3 means tongue tied. ChaCha!

  • Source: http://www.chacha.com/question/what-does-college-basketball-ncaa-stand-for-or-mean

    Black Ops 2

    মঙ্গলবার, ২ জুলাই, ২০১৩

    Challenge to stop resumption of same-sex marriages in California

    Gay marriages resume in California with a flurry

    newsday.com (1 day ago)

    Same-sex marriages resume in state

    appeal-democrat.com (1 day ago)

    More Home news ?

    Source: http://home.topnewstoday.org/home/article/6643092/

    Sequester

    New treatment for schizophrenia?

    July 1, 2013 ? A research group led by professor Jesper Ekelund showed that by giving a very large dose of famotidine (200 mg daily), sufficient amounts of the drug are able to penetrate the so-called blood-brain barrier to affect the histamine system in the brain.

    Famotidine has been used for the treatment of heartburn since the 1980s, but at regular dosing, famotidine almost does not enter the brain at all, since the brain is protected by the blood-brain barrier. By increasing the dosage five-fold the drug is able to enter the brain and affect the histamine system.

    "Already after one week the symptoms of persons suffering from schizophrenia started to decrease and after four weeks of treatment the symptoms had decreased statistically significantly. The patients that participated in the study were also positively disposed towards the treatment," says Ekelund.

    Thirty persons suffering from schizophrenia participated in the study. The patients had been on sickness pension for at least five years and were randomly divided into two groups, one which received famotidine and one which received placebo. All of the patients who took famotidine responded positively to the treatment while the symptoms of those who were on a placebo did not change.

    Schizophrenia is the most common and severe psychotic disorder, and is the cause of at least half of all psychiatric hospital treatment days. No randomized, controlled trials in humans that test the effect of H2 blockade in schizophrenia have been published so far.

    Innovation in psychiatric medication urgently needed

    Since 1963, when the subsequent Nobel prize winner Arvid Carlsson showed that dopamine has a central role in psychosis, the so called dopamine-hypothesis has been central in psychosis. All presently available medications for psychosis are based around this principle. Since treatment response is all too often incomplete and side effects common, there is still a great, unmet medical need for medications with other mechanisms of action. Many other signaling substances have been the focus of attention, but so far, the brain histamine system has most widely been regarded as important only with regard to side effects of many psychosis medications.

    "Famotidine shouldn't be used directly as treatment for schizophrenia until long-term use of a dose of this size has been proved safe. However, our study shows that the histamine system in the brain offers a novel approach to treating psychosis. This should lead to increased efforts by the pharmaceutical industry to develop medications based on this histamine-based mechanism," says Ekelund.

    Famotidine works by blocking the histamine H2 receptor. There are important neurons in the brain that use histamine as their primary signaling substance. These neurons have an important role as regulators of other signaling substances. From animal research, it is known that by affecting the histamine system, one can also affect other signaling substances that are known to be involved in schizophrenia.

    The project has already received international recognition. Katarina Meskanen, one of the members of Ekelunds research group, was awarded the Young Scientist Award of the SCNP (Scandinavian College of Neuropsychopharmacology) and the project has been awarded substantial funding (306,000 USD) from the Stanley foundation for follow-up studies.

    The research group will replicate the finding through a larger, multinational study in collaboration with Karolinska Institutet in Sweden, where the study is coordinated by professor Jari Tiihonen.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/5ynH-ojEZuA/130701080938.htm

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